In this paper, we obtain a property of the expectation of the inverse of compound Wishart matrices which results from their orthogonal invariance. Using this property as well as results from random matrix theory (RMT), we derive the asymptotic effect of the noise induced by estimating the covariance matrix on computing the risk of the optimal portfolio. This in turn enables us to get an asymptotically unbiased estimator of the risk of the optimal portfolio not only for the case of independent ob...