We formulate and compute a class of mean-field information dynamics for reaction-diffusion equations. Given a class of nonlinear reaction-diffusion equations and entropy type Lyapunov functionals, we study their gradient flows formulations with generalized optimal transport metrics and mean-field control problems. We apply the primal-dual hybrid gradient algorithm to compute the mean-field control problems with potential energies. A byproduct of the proposed method contains a new and efficient v...