In this paper, we propose a market model with returns assumed to follow a multivariate normal tempered stable distribution defined by a mixture of the multivariate normal distribution and the tempered stable subordinator. This distribution is able to capture two stylized facts: fat-tails and asymmetry, that have been empirically observed for asset return distributions. On the new market model, we discuss a new portfolio optimization method, which is an extension of Markowitz's mean-variance opti...